We have a fully-funded PhD opportunity at the MRC Laboratory of
Molecular Biology to develop live-cell hyperspectral microscopy and
apply it to the analysis of endosomal sorting and fission, with an
October 2020 or January 2021 start. I would be grateful if you could
forward the details below to anyone who you think may be interested.
Many thanks and best wishes,
In this project, you will develop a new, fast hyperspectral imaging
system coupled to a high-performance oblique plane light sheet
microscope. This system will simultaneously visualise eight or more
fluorescently-tagged molecular species at video rates, enabling live
cell 3D hyperspectral imaging. After an initial year of development and
testing, this system will be used to analyse the complex events of
endosomal sorting and fission in live cells and ultimately organisms. In
particular, you will make use of CRISPR lines expressing the proteins of
interest fused to fluorescent tags at an endogenous level. This project
would suit those with backgrounds in physics, biology, biophysics or
bioengineering. A keen interest in both instrumentation development and
solving fundamental biological questions is essential.
More details, including how to apply, can be found via
https://bit.ly/3as4s2C. Application deadline: 31 May 2020.
MRC Laboratory of Molecular Biology
Cambridge CB2 0QH, UK
+44 (0)1223 267776